Riepilogo rapido

Tipo di medicinale

Hormone replacement therapy (HRT) containing estradiol, a natural oestrogen.

Funziona tramite

Oestrogel contains estradiol, an oestrogen identical to that naturally produced by the ovaries. It works by restoring oestrogen levels in postmenopausal women, helping to relieve symptoms related to hormonal deficiency such as hot flushes, night sweats, vaginal dryness, and sleep disturbances.

Principio attivo

Estradiol

Efficace entro

You may notice an improvement in symptoms within the first few weeks, but it typically takes 8 to 12 weeks of consistent use to fully rejuvenate the vaginal lining and eliminate dryness or pain.

Generico?

Yes

Effetti collaterali

Vagifem is very well tolerated because the hormone dose is extremely low. Common: Mild discharge or irritation in the first few weeks. Rare: Headache or abdominal pain. Note: Unlike oral HRT, Vagifem does not carry the same risks regarding blood clots because it is not absorbed systematically into the whole body.

Dettagli del medicinale

Descrizione

Vagifem è il trattamento topico originale, clinicamente provato, per la secchezza vaginale e il disagio associati alla menopausa. Prodotto da Novo Nordisk, è ampiamente considerato il "gold standard" nella terapia ormonale sostitutiva locale.

Ogni compressa di Vagifem contiene 10 microgrammi di estradiolo e viene fornita con un applicatore monouso pre-caricato unico. Questo design igienico garantisce che la compressa venga posizionata correttamente e comodamente ogni volta. Poiché tratta i sintomi localmente senza aumentare significativamente i livelli di estrogeni nel sangue, è una scelta sicura ed efficace per un sollievo a lungo termine.

Ingredienti

Active ingredient: Estradiol hemihydrate (10 micrograms). Excipients: Hypromellose, lactose monohydrate, maize starch, magnesium stearate. Film-coating: Hypromellose, macrogol 6000.

Effetti collaterali

Breast tenderness, bloating, nausea, headaches, mood changes, or light vaginal bleeding may occur.
Less commonly: fluid retention, skin rashes, weight gain, or irritation at the application site.
Contact a doctor immediately if you experience chest pain, shortness of breath, jaundice, or sudden swelling of the legs.

Avvertenze

Do not use Oestrogel if you have breast cancer, endometrial cancer, unexplained vaginal bleeding, a history of thromboembolic disease, or severe liver disease.

In women with an intact uterus, treatment must be combined with a progestogen for 12 to 14 days per 28-day cycle to reduce the risk of endometrial hyperplasia.

Contact your doctor immediately if you experience chest pain, shortness of breath, swelling of the legs, or jaundice.

Domande Frequenti

Does this medication enter my bloodstream?

Vagifem is a "local" treatment. While a tiny amount of oestrogen may be absorbed, the vast majority stays in the vaginal tissue where it is needed. This is why it is considered safer than tablets or patches for women who only have vaginal symptoms.

Can I have sex while using this?

Yes. Vagifem helps restore lubrication and elasticity, making intercourse more comfortable. It is best to insert the tablet after sexual activity (before going to sleep) so that it stays in place overnight.

Is there a difference between Vagifem and Vagirux?

Only in branding and packaging. Vagifem is the original brand by Novo Nordisk, while Vagirux is a generic version. Both contain the exact same active ingredient (10mcg estradiol) and work in the same way. Some women prefer Vagifem for its specific applicator design or simply because they are used to the brand.

Do I need to take Progesterone with this?

Generally, No. Because the dose is local and very low, it usually does not affect the lining of the womb. Therefore, most doctors do not require you to take additional progesterone (like Utrogestan) if you are only using Vagifem.

Is the applicator reusable?

No. One of the key benefits of Vagifem is that each tablet comes in its own sterile, disposable applicator. You use it once to insert the tablet and then throw the plastic applicator away. This ensures maximum hygiene.

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