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Quick summary

Type of medicine

Topical retinoid and benzoyl peroxide gel

Works by

Works by increasing skin cell turnover, unclogging pores, and reducing the bacteria and inflammation involved in acne.

Active ingredient

Adapalene, Benzoyl Peroxide

Effective within

Visible improvement typically occurs after 4 weeks of consistent use.

Generic?

No

Side effects

Dry skin, irritant contact dermatitis, burning sensation, skin irritation, redness of the skin, peeling.

How it works

Clinician-led care, designed to be simple from start to finish.

1
Step 1

Check eligibility

Answer a short 2-minute questionnaire so we can understand your goals and medical history.

2
Step 2

Doctor approval

If eligible, one of our doctors issues your free prescription within 24 hours.

3
Step 3

Fast delivery, ongoing support

Next-day delivery across the EU, with support at every step of your treatment.

Medication details

Description

Effezel is a potent dual-action gel used to treat acne with comedones (blackheads) and papules (inflammatory spots).

It combines two active ingredients: Adapalene (a retinoid that unblocks pores and reduces inflammation) and Benzoyl Peroxide (an antimicrobial agent that kills acne-causing bacteria and softens the outer layer of the skin). This combination targets acne on multiple fronts, making it more effective for inflammatory acne than using single ingredients alone.

Ingredients

1 g of gel contains: Adapalene 1 mg (0.1% w/w) and hydrous benzoyl peroxide, equivalent to 25 mg (2.5% w/w) anhydrous benzoyl peroxide. Excipients: Disodium edetate, Docusate sodium, Glycerol, Poloxamer, Propylene glycol (E1520), Simulgel 600PHA (copolymer of acrylamide and sodium acryloyldimethyltaurate, isohexadecane, polysorbate 80 (E433), sorbitan oleate), Purified water.

Frequently Asked Questions

Will this bleach my clothes or towels?

Yes. This is an important precaution. Effezel contains benzoyl peroxide, which has a strong bleaching effect on colored fabrics (towels, bed linen, pajamas) and hair. The stains are permanent. Wash your hands thoroughly after application, let the gel dry completely before dressing, and use a white pillowcase to prevent damage.

Is skin irritation normal when starting?

Yes, irritation is common, especially in the first few weeks. Because this gel contains two drying ingredients, you may experience redness, burning, dryness, or peeling. To manage this, apply a non-comedogenic moisturizer daily. If the irritation is severe, you can apply the gel every other night until your skin builds up tolerance.

Why does my skin look worse at first?

You may experience a "purging" phase during the first few weeks. The Adapalene in the gel accelerates skin renewal, bringing deep-seated impurities to the surface rapidly. While this looks like a new breakout, it is actually the medication cleaning out your pores. Stick with the treatment; it usually improves after this initial phase.

Can I use this during pregnancy?

No. Effezel contains Adapalene, which is a retinoid. The use of retinoids is contraindicated during pregnancy due to potential risks to the unborn baby. If you become pregnant or plan to become pregnant, you should discontinue use and consult your doctor for a safer alternative.

Do I need to avoid the sun?

Yes. Both active ingredients can make your skin more sensitive to sunlight and increase the risk of sunburn. Avoid sunbeds and limit sun exposure. Even on cloudy days, it is recommended to use a sunscreen (SPF 30 or higher) on the treated areas if you go outside. Apply the gel strictly in the evening.

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